Does human exposure to aluminum play a role in autism spectrum disorders (ASD)? Research at Keele University published in the Journal of Trace Elements in Medicine and Biology provides the strongest indication that aluminum is an etiological agent in ASD. The aluminum content of brain tissue from 5 donors who died with the diagnosis of ASD was found to be extremely high, some of the highest values that were still measured in human brain tissue.
For example, why should the occipital lobe of a 15-year-old boy with autism be 8.74 (11.59) micrograms / g dry weight, a value at least 10 times higher than could be considered acceptable for an adult, late are a child? Although the ammonium content of each of the 5 brains was shockingly high, it was the location of the aluminum in the brain tissue that served as the most striking observation.
Most of the aluminum was identified in non-neuronal cells, including microglia and astrocytes. Aluminum was also found in lymphocytes in the meninges and in similar inflammatory cells in the vasculature. There was clear evidence that inflammatory cells heavily loaded with aluminum enter the brain through the meningeal membranes and the blood-brain barrier.
The fact that the majority of the aluminum in brain tissue in ASD was intracellular and associated with non-neuronal cells is, at least for the time being, unique to ASD and can begin to explain why young adolescents had so much aluminum in their bodies.
Perhaps there is something in the genetic makeup of specific individuals that makes them susceptible to accumulating and retaining aluminum in their brains, as is also suggested for individuals with familial Alzheimer’s. The new evidence strongly suggests that aluminum enters the ASD via pro-inflammatory cells that are full of aluminum in the blood and / or lymph, as has been demonstrated for monocytes at vaccine injection sites including aluminum adjuvants. Perhaps we now have the alleged link between vaccination and ASD, where the link is the inclusion of an aluminum adjuvant in the vaccine.